Study to Evaluate t(11;14) Status and BCL2 Expression in Adult Participants With Multiple Myeloma (MM)

Study Identifier
H20-126
CT.gov Identifier
NCT04721002
EudraCT Identifier
Not available
EUCTIS ID
Not available
For general inquiries, please contact

844-663-3742 or [email protected]

Study Complete

Study Details

Medical Condition
  • Blood Cancer - Multiple Myeloma
    • Study Drug
    N/A
    Phase
    N/A
    Sex
    Female & Male
    Age
    18+ years
    Inclusion and Exclusion Criteria
    Inclusion Criteria:
    \- Confirmed newly diagnosed or relapsed/refractory (R/R) Multiple myeloma (MM) who have signed informed consent for the use of their biological material for research purposes.
    Exclusion Criteria:
    \- Participants who do not have Bone Marrow (BM) and blood sample at time of diagnosis or at confirmation of relapse.

    Protocol Summary

    Multiple myeloma (MM) is a rare cancer caused by abnormal survival of plasma cells (blood cells). Most trial participants with MM relapse (cancer has come back) or become non- responsive to treatment and remission gets shorter after each line of treatment. This is a study to assess t(11;14) and BCL2 expression in adult participants with newly diagnosed and relapsed/refractory (R/R) MM.

    Approximately 500 adult participants with newly confirmed or relapsed/refractory (R/R) multiple myeloma (MM) will be enrolled in around 15-20 countries.

    Participants will receive standard of care while participating in this study. No drug will be administered as a part of this study.

    Participants will attend regular visits during the course of the study at a hospital or clinic and will be asked to provide bone marrow and blood samples.

    Study Locations

    Location
    Status
    Location
    Tulane School of Medicine /ID# 223864
    New Orleans, Louisiana, United States, 70112
    Status
    Not applicable
    Location
    University of Texas Southwestern Medical Center /ID# 223865
    Dallas, Texas, United States, 75390-7208
    Status
    Not applicable
    Location
    Hospital Italiano de Buenos Aires /ID# 224153
    Ciudad Autonoma Buenos Aires, Buenos Aires F.D., Argentina, 1199
    Status
    Not applicable
    Location
    Alfred Health /ID# 224386
    Melbourne, Victoria, Australia, 3004
    Status
    Not applicable
    Location
    Hospital São Rafael /ID# 224307
    Salvador, Estado de Bahia, Brazil, 41253-190
    Status
    Not applicable
    Location
    Hospital de Clinicas de Porto Alegre /ID# 224274
    Porto Alegre, Rio Grande Do Sul, Brazil, 90035-903
    Status
    Not applicable
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