Efficacy and Safety of ABT-874 in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study Identifier
M05-736
CT.gov Identifier
NCT00292396
EudraCT Identifier
Not available
EUCTIS ID
Not available
For general inquiries, please contact

844-663-3742 or [email protected]

Study Complete

Study Details

Medical Condition
  • Dermatology - Psoriasis (PsO)
    • Study Drug
  • Anti IL-12 monoclonal antibody/ABT-874
  • placebo
    • Phase
    Phase 2
    Sex
    Female & Male
    Age
    18+ years
    Inclusion and Exclusion Criteria
    Inclusion Criteria:
    * Subject was age 18 or older and in good health (Investigator discretion) with a recent stable medical history. * Subject had a clinical diagnosis of psoriasis for at least 6 months, and had moderate to severe plaque psoriasis
    Exclusion Criteria:
    * Subject had previously received systemic or biologic anti-IL-12 therapy * Subject cannot discontinue systemic therapies and/or topical therapies for the treatment of psoriasis and cannot avoid UVB or PUVA phototherapy * Subject is taking or requires oral or injectable corticosteroids * Subject considered by the investigator, for any reason, to be an unsuitable candidate for the study * Female subject who is pregnant or breast-feeding or considering becoming pregnant

    Protocol Summary

    The purpose of the study is to assess the safety and efficacy of ABT-874 in the treatment of moderate to severe chronic plaque psoriasis.

    Study Locations

    Location
    Status
    Location
    Site Reference ID/Investigator# 3351
    San Diego, California, United States, 92123
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 3347
    Alpharetta, Georgia, United States, 30022
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 3348
    Skokie, Illinois, United States, 60077
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 993
    Indianapolis, Indiana, United States, 46256
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 990
    Boston, Massachusetts, United States, 02114
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 3349
    St Louis, Missouri, United States, 63117
    Status
    Not applicable
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