Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood

Study Identifier
M10-158
CT.gov Identifier
NCT00616772
EudraCT Identifier
Not available
EUCTIS ID
Not available
For general inquiries, please contact

844-663-3742 or [email protected]

Study Complete

Results Available

Scientific Result Summary
Available Language(s): English
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Study Details

Medical Condition
  • Cardiovascular Disease
  • Dyslipidemia
    • Study Drug
  • ABT-335
  • Placebo
    • Phase
    Phase 3
    Sex
    Female & Male
    Age
    45+ years
    Inclusion and Exclusion Criteria
    Inclusion Criteria:
    * Patients with mixed dyslipidemia * Qualifying cIMT thickness
    Exclusion Criteria:
    * Patients with certain chronic or unstable medical conditions. * Patients with unstable dose of medications or receiving coumadin, cyclosporine, or certain other medications * Pregnant or lactating women or women intending to become pregnant * Patients with diabetes mellitus that is poorly controlled

    Protocol Summary

    The primary purpose of this study is to test the effect and safety of once daily ABT-335 on the thickness of the lining of the carotid artery (a blood vessel to the brain) in patients with abnormal blood lipids who have optimal levels of low density lipoprotein cholesterol ("bad cholesterol") after taking atorvastatin.

    Study Locations

    Location
    Status
    Location
    Site Reference ID/Investigator# 6747
    Chandler, Arizona, United States, 85225
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 7089
    Gilbert, Arizona, United States, 85295
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 7097
    Mesa, Arizona, United States, 85206
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 26394
    Phoenix, Arizona, United States, 85032
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 6848
    Scottsdale, Arizona, United States, 85251
    Status
    Not applicable
    Location
    Site Reference ID/Investigator# 7059
    Tempe, Arizona, United States, 85282
    Status
    Not applicable
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