A Study of Veliparib in Combination With Carboplatin and Paclitaxel in Japanese Subjects With Solid Tumors

Study Identifier
M12-629
CT.gov Identifier
EudraCT Identifier
Not available
EUCTIS ID
Not available
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Study Complete

Study Details

Medical Condition
  • Solid Tumors (General)
  • Study Drug
  • veliparib (ABT-888)
  • carboplatin
  • paclitaxel
  • Phase
    Phase 1
    Sex
    Female & Male
    Age
    20 - 99 Years

    Protocol Summary

    This is a Phase 1 open-label study and consists of 3 treatment groups (dose levels) . Treatment cycles are 3 weeks in duration. The primary objective of this study is to determine the recommended phase two dose (RPTD) of veliparib (ABT-888) when administered in combination with carboplatin and paclitaxel in Japanese subjects with solid tumors. Secondary objectives are to assess pharmacokinetics and to obtain a preliminary efficacy of anti-tumor activity in the subjects.

    Study Locations

    Location
    Status
    Location
    Site Reference ID/Investigator# 68622
    Tokyo, Japan
    Status
    Not applicable