Pharmacokinetics and Safety of ABT-493 and ABT-530 in Subjects With Normal and Impaired Renal Function

All Subjects * Females must have negative results for pregnancy tests performed: * At Screening on a urine specimen, and * On a serum sample obtained on Study Day -2 (prior to dosing). * Body Mass Index (BMI) is ≥ 18 to ≤ 38 kg/m2, inclusive. * Body Weight \> 50 kg. Subjects with Normal Renal Function In addition to the main inclusion criteria above for all subjects, the following criteria must be met for subjects with normal renal function enrolled in Group 5: * Judged to be in general good health based upon the results of a medical history, physical examination, and 12-lead electrocardiogram (ECG). * At screening, estimated GFR (by MDRD equation) should be ≥ 90 mL/min/1.73 m2. Subject with Renal Impairment In addition to the main inclusion criteria for all subjects, the following criteria must be met for all subjects with renal impairment enrolled in Groups 1, 2, 3, 4 and 6: * Judged to be in stable condition and acceptable for study participation based upon the results of a medical history, physical examination, laboratory profile and ECG. * Presence of chronic renal impairment as indicated by medical history and a screening estimated GFR (by MDRD equation) \< 90 mL/min/1.73 m2. * Subjects with ESRD undergoing hemodialysis should have been receiving dialysis for at least 1 month.

- History of significant sensitivity to any drug. * Pregnant or breastfeeding female. * Recent (6-month) history of drug or alcohol abuse. * Positive test result for hepatitis A virus immunoglobulin M (HAV-IgM), hepatitis B surface antigen (HBsAg) or hepatitis C virus antibody (HCV Ab) or HIV antibodies (HIV Ab). Negative HIV status will be confirmed at Screening and the results will be maintained confidentially by the study site. * Subjects on strict vegetarian diet.