SC-004 Alone or With ABBV-181 in Subjects With Epithelial Ovarian, Fallopian Tube, Primary Peritoneal and Endometrial Cancers

Study Identifier
M16-553
CT.gov Identifier
EudraCT Identifier
Not available
EUCTIS ID
Not available
For general inquiries, please contact

Study Details

Medical Condition
  • Cancer - Other
  • Study Drug
  • SC-004
  • ABBV-181
  • Phase
    Phase 1
    Sex
    Female
    Age
    18+ years

    Protocol Summary

    This is a two-part study consisting of Part A (dose regimen finding) followed by Part B (dose expansion). Part A (dose regimen finding) will allow definition of the maximum tolerated dose (MTD) through dose escalation and possible dose interval modification. In Part B (dose expansion), potential therapeutic doses may be studied with SC-004 as monotherapy and SC-004 in combination with ABBV-181 in disease-specific cohorts.

    Study Locations

    Location
    Status
    Location
    University of Alabama /ID# 202249
    Birmingham, Alabama, United States, 35294
    Status
    Not applicable
    Location
    Highlands Oncology Group /ID# 209165
    Fayetteville, Arkansas, United States, 72703-4005
    Status
    Not applicable
    Location
    City of Hope /ID# 202493
    Duarte, California, United States, 91010
    Status
    Not applicable
    Location
    University of Chicago /ID# 200735
    Chicago, Illinois, United States, 60637
    Status
    Not applicable
    Location
    Henry Ford Health System /ID# 202480
    Detroit, Michigan, United States, 48202
    Status
    Not applicable
    Location
    Mayo Clinic - Rochester /ID# 200732
    Rochester, Minnesota, United States, 55905-0001
    Status
    Not applicable
    Showing {first} - {last} of {total} Results